FRIDAY, Sept. 23, 2022 (HealthDay News) -- Insomnia may increase the likelihood of subjective memory decline in middle-aged and older adults, according to a study published online July 25 in SLEEP.
Jean-Louis Zhao, from the University of Montreal, and colleagues examined the longitudinal association between probable insomnia status and both subjective and objective memory decline in middle-aged and older adults (45 years and older). The analysis included 26,363 participants followed for three years.
The researchers observed an increased odds of self-reported memory worsening for participants free of insomnia at baseline who developed probable insomnia disorder at follow-up versus those who developed insomnia symptoms only or remained free of insomnia symptoms (odds ratio, 1.70). Increased odds also were observed for subjective memory worsening at follow-up among participants whose sleep worsened from baseline to follow-up (odds ratio, 1.22) versus those who remained insomnia-free or improved their sleep. On neuropsychological tests, there were no significant associations noted between the development of probable insomnia disorder or worsening sleep and performance.
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"These findings of an increased odds for subjective memory decline in middle-aged and older adults with insomnia disorder suggest insomnia may be an important target for early interventions addressing age-related cognitive decline," the authors write.
Several authors disclosed financial ties to pharmaceutical and health-related companies.